Work

Anterior-Posterior Connectivity within the Default Mode Network Increases During Maturation.

Year: 2015

Type: article

Abstract: < 0.05), specifically the anterior cingulate cortex/medial prefrontal cortex (ACC/mPFC) and PCC nodes and the left IPL and right MTG nodes. The correlation between ACC/mPFC ↔ PCC connectivity and age was more significant than the correlation between left IPL ↔ right MTG connectivity and age by more than an order of magnitude. We suggest that these changes in functional connectivity in part underlie the introspective mental changes known to commonly occur between the preadolescent and adult years. A range of neurological and psychological conditions that hamper social interactions, from ASD to psychopathy, may be marked by deviations from this maturational trajectory.

Source: PubMed

Authors: Stuart D Washington, John W VanMeter

Institution: Georgetown University Medical Center

Language: English

Topic: Functional Brain Connectivity Studies

Subfield: Cognitive Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institute of Mental Health, National Center for Research Resources, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: Neurobiologic Origins and Innovative Treatment of Autism, Postdoctoral Training in Developmental Disabilities Research, General Clinical Research Center, IDDRC at Children's Research Institute