Joint hypermobility in fibromyalgia patients has no impact on tests for disease severity
Year: 2008
Type: article
Study design: Observational Study
Abstract: Benign joint hypermobility appears more frequently in fi bromyalgia patients than in a comparable healthy cohort. The aim of this study was to investigate if fi bromyalgia patients also diagnosed with benign joint hypermobility may be a distinct subgroup in the fi bromyalgia population.The presence of benign joint hypermobility was determined in a population of 27 fi bromyalgia patients. Relevant anatomical, physiological and biochemical parameters were measured, and specifi c fi bromyalgia criteria were assessed for each patient. 15 patients suff ered from benign joint hypermobility. In general, the presence of benign joint hypermobilty did not change the disease appearance in fi bromyalgia patients. This applied to the main characteristics - pain (p=0.6), muscle strength (p=0.6), hydroxyproline in skin (p=0.99), or collagen markers in urine CTX-I and CTX-II (p=0.45 and 0.41, respectively) - as well as to other studied variables. The only diff erence found between the two groups was in concentrations of plasma electrolytes with a higher potassium concentration level and lower sodium to potassium ratio in the hypermobile group (p=0.026), which showed the same mean as seen in the healthy population. Benign joint hypermobility with fi bromyalgia does not change the fi bromyalgia disease characteristics, and hypermobile fi bromyalgia patients do not appear to diff er in disease severity from the rest of the fi bromyalgia population.
Institution: Frederiksberg Hospital
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W108971713