Work

Physiology and Pathophysiology of Gallbladder Motility

Year: 1993

Type: review

Abstract: Gallbladder motility is controlled by a complex interplay of hormonal and neural factors. It is being recognized increasingly that the key mediators of gallbladder motility—the gastrointestinal peptides—act through both neural and hormonal pathways to influence gallbladder motility. Most significant gallbladder disease is associated with disturbances of normal motility. Experimental and clinical studies have demonstrated impaired motility in gallstone disease, and experimental evidence indicates that motility disturbances precede gallstone formation. Acute acalculous cholecystitis is seen frequently in patients with prolonged fasting and gallbladder stasis, and chronic acalculous cholecystitis actually is defined by demonstrable decreased gallbladder emptying.

Source: Surgical Clinics of North America

DOI: 10.1016/s0039-6109(16)46191-8

Authors: Sean Tierney, Henry A. Pitt, Keith D. Lillemoe

Institutions: Johns Hopkins University, Johns Hopkins Medicine, Johns Hopkins Hospital

Language: English

Topic: Gallbladder and Bile Duct Disorders

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,190