Year: 2003
Type: article
Abstract: Chromatin is highly dynamic structure that plays essential role in regulating nuclear processes that utilize the DNA template including DNA repair,replication, transcription and recombination.Thus,the mechanisms by which chromatin structures are assembled and modified are questions of broad interest. Chromatin structure is linked to transcriptional regulation, and recent studies show how chromatin is altered so as to facilitate transcription. In addition, modification of chromatin structure is an important regulatory mechanism. Here I review the mechanism of chromatin assembly in vitro and the changes of chromatin structure related to transcriptional activation.
Author: Takashi Ito
Institution: Nagasaki University
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W112378534