Buffering Effects of General and Medication-Specific Social Support on the Association Between Substance Use and HIV Medication Adherence
Year: 2011
Type: article
Abstract: The success of highly active antiretroviral therapy (HAART) among persons living with HIV is largely dependent on strict medication adherence. Recent research suggests that alcohol and other drug use (AOD) may be an important barrier to HAART adherence. In this study, we examined the impact of AOD on HAART adherence as well as the moderating effects of general and medication-specific social support. The data were collected as part of a longitudinal randomized control trial with 224 HIV-positive patients at an HIV primary care clinic in the northwestern United States. Findings indicated that AOD use was negatively associated with HAART adherence and that medication-specific (but not general) social support moderated the AOD-adherence association at 3 (but not at 6 or 9) months. Results indicate the importance of medication-specific social support to treat comorbid AOD use and HIV; implications for future research and intervention programs for HIV-positive AOD users are discussed.
Source: AIDS Patient Care and STDs
Institution: University of Washington
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: Peer & Pager Support to Enhance Antiretroviral Adherence, Mentoring Diverse Scientists in HIV Research on Substance Abuse and Mental Health, Center for Studies in Demography and Ecology, University of Washington/Fred Hutch Center for AIDS Research, The ITZA Program: Indigenous HIV/AIDS Research Training 3 (IHART3) Program
OpenAlex ID: W112621234