Physical activity and brain plasticity in late adulthood
Year: 2013
Type: article
Abstract: The human brain shrinks with advancing age, but recent research suggests that it is also capable of remarkable plasticity, even in late life. In this review we summarize the research linking greater amounts of physical activity to less cortical atrophy, better brain function, and enhanced cognitive function, and argue that physical activity takes advantage of the brain's natural capacity for plasticity. Further, although the effects of physical activity on the brain are relatively widespread, there is also some specificity, such that prefrontal and hippocampal areas appear to be more influenced than other areas of the brain. The specificity of these effects, we argue, provides a biological basis for understanding the capacity for physical activity to influence neurocognitive and neuropsychiatric disorders such as depression. We conclude that physical activity is a promising intervention that can influence the endogenous pharmacology of the brain to enhance cognitive and emotional function in late adulthood.
Institution: University of Pittsburgh
Language: English
Topic: Physical Activity and Health
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
Awards: Influence of Physical Activity and Weight Loss on Brain Plasticity, ACISR for Late-Life Depression Prevention, Alzheimer's Disease Research Center, University of Pittsburgh Clinical and Translational Science Institute, The Effects of Bipolar Disorder and its Comorbidities on Cognition in Older Adult, Amyloid, white matter hyperintensities & outcomes of late-life depression, Pittsburgh Older Americans Independence Center
OpenAlex ID: W4322697583