Year: 2010
Type: dissertation
Abstract: Formation of ozonation products of pharmaceutical compounds bezafibrate and carbamazepine was studied under four varying ozone and hydroxyl radical exposures under typical drinking water ozonation treatment. The results indicate that the concentration of carbamazepine was reduced to below method detection limit within 2 minutes of ozonation. Oxidation efficiency of bezafibrate exceeded 95% after 5 min of ozonation in all settings. Direct attack by ozone was responsible for oxidation of carbamazepine under all experimental conditions. Major ozonation products of carbamazepine were observed to be susceptible to oxidation by hydroxyl radicals. Oxidation of bezafibrate and product formation was affected by both ozone and hydroxyl radical exposure, depending on their relative magnitude. While one of ozonation products of bezafibrate by direct attack of ozone was observed to be relatively resistant to further oxidation, the others were either completely or partially transformed mostly through reaction by hydroxyl radicals.
Author: Leila Tootchi
Institution: University of Windsor
Language: English
Subfield: Water Science and Technology
Field: Environmental Science
Domain: Physical Sciences
Open Access status: green
Funder: Ministry of Education, India
OpenAlex ID: W121753555