Microglial and Astrocytic Reactions in Alzheimer’s Disease
Year: 2002
Type: book-chapter
Abstract: In the last 20 years, there have been major advances in understanding the causes of Alzheimer’s disease (AD) that have allowed the development of different treatment strategies. Progress has been particularly rapid since 1984, with the determination of the amino acid sequence of the amyloid beta (Aβ) peptide in cerebrovascular amyloid (1), and plaque cores (2). From this finding, the identification of the amyloid precursor protein (and its gene), (3,4,5) as being the protein from which plaque Aβ is derived, was possible.
Source: Humana Press eBooks
Authors: Douglas G. Walker, Thomas G. Beach
Language: English
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W122055635