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New approach to identify ischemic stroke patients at risk to develop hemorrhagic transformation.

Year: 2012

Type: article

Abstract: Some patients with ischemic stroke are subject to hemorrhagic transformation, a complication leading to increased patient morbidity and mortality. The discovery of biomarkers that can be used to identify ischemic strokes prone to this complication are very important for the clinical practice because therapy could be altered to mitigate the risk. We discuss here the results of a trial that evaluated for the first time tight junction proteins as biomarkers of blood-brain barrier disruption and hemorrhagic transformation in ischemic stroke.

Source: Europe PMC (PubMed Central)

Authors: Bogdan Nicolae Manolescu, Glen C Jickling

Institution: Universitatea Națională de Știință și Tehnologie Politehnica București

Language: English

Topic: Acute Ischemic Stroke Management

Subfield: Clinical Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W123423447

FWCI:

Cites: 13

Cited by: 1

Related to: 10