Work

New dopamine agonist pramipexole improves parkinsonism and depression in Parkinson's disease.

Year: 2011

Type: article

Abstract: Previous studies have shown that pramipexole might have the potential to improve depressive symptoms in patients with Parkinson's disease. To provide more evidence, in five Japanese patients at Hoehn & Yahr stage 1-3 we evaluated the Unified Parkinson's Disease Rating Scale (UPDRS), Hamilton Depression Rating Scale (HAMD) and Montgomery Asberg Depression Rating Scale (MADRS) at our hospital. After the pramipexole treatment, each total score of UPDRS, HAMD and MADRS significantly decreased compared with that before the treatment. Our data indicate that pramipexole improves depressive symptoms in patients with Parkinson's disease.

Source: PubMed

Authors: Toshihide Harada, Fumiko Ishizaki, Nobuko Horie, Yumiko Nitta, Tohru Yamada, Tomohiro Sasaki, Tomoomi Nagakane, Yoshiteru Yasumatsu, Kohsaku Nitta, Hiroyuki Katsuoka

Institution: Prefectural University of Hiroshima

Language: English

Topic: Parkinson's Disease Mechanisms and Treatments

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W1261937870

FWCI: 0.55

Cites: 8

Cited by: 10

Related to: 10