The placental transfer of IgG subclasses in human pregnancy.
Year: 1980
Type: article
Study design: Observational Study
Abstract: Total IgG concentrations and the concentrations of the four subclasses of IgG were estimated in thirty-four pairs of maternal and foetal sera from pregnancies of various gestations ranging from 28 to 42 weeks using the method of radial immunodiffusion. It was found that: (1) all subclasses of IgG cross the human placenta freely, (2) foetal levels of IgG and each subclass of IgG exceed maternal levels in full-term pregnancies and (3) there was a close linear relationship between gestational age and the placental transfer of IgG and each of its subclasses.
Source: PubMed Central
Authors: R W Pitcher-Wilmott, P Hindocha, C B Wood
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W128915242