Sleep-Disordered Breathing, Physiological Sequelae, and the Neurobiological Relationship with Psychopathology
Year: 2009
Type: dissertation
Abstract: Sleep-Disordered Breathing is empirically related to at least three forms of mental illness: Autistic Disorder (AD), Attention Deficit/Hyperactivity Disorder (ADHD), and Major Depressive Disorder (MDD).A review of the literature revealed that SDB and/or its correlates are both cause and effect of critical neurobiological mechanisms contributing to these forms of psychopathology during gestation, childhood/adolescence, and adulthood, respectively.Time-specific SDB sequelae correlate with cortical alterations that mirror the known neuroanatomical signatures of the aforementioned mental illnesses.Thus, SDB may be not only a general risk factor for psychopathology but a specific risk factor for at least three types of mental illness when viewed in its age-specific developmental context.Since in many cases SDB is readily treatable, implications of this theory include a number of treatment strategies for diverse types of psychopathology.
Author: Daniel Ehrmann
Language: English
Subfield: Physiology (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W129004070