Work

Regulation of cytosolic acetoacetyl coenzyme A thiolase, 3-hydroxy-3-methylglutaryl coenzyme A synthase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and mevalonate kinase by low density lipoprotein and by 25-hydroxycholesterol in Chinese hamster ovary cells.

Year: 1980

Type: article

Abstract: Chinese hamster ovary; De-S, delipidated fetal calf serum; MeiSO, dimethyl sulfoxide; HDL, high density lipoprotein; 25-OH cholesterol, 25-hydroxycholestero1; HMG-CoA, 3-hydroxy-3-methyglutaryl coenzyme A; LP(-), lipoprotein-deficient serum; GLC, gas-liquid chromatography; TLC, thin layer chromatography.'I Determined according to published procedure (12) using lactate Determined according to published procedure (12) using citrate n.d., not determined.dehydrogenase as cytoplasmic enzyme marker.synthase as mitochondrial enzyme marker.

Source: Journal of Biological Chemistry

DOI: 10.1016/s0021-9258(19)43901-x

Authors: T.Y. Chang, J.S. Limanek

Institution: Dartmouth College

Language: English

Topic: Cholesterol and Lipid Metabolism

Subfield: Biochemistry

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,430