Immune Response to HTLV-I and HTLV-II
Year: 2001
Type: book-chapter
Abstract: Originally identified from a T-lymphoblastoid cell line (HUT 102) of a patient diagnosed with a cutaneous T-cell lymphoma, the human T-lymphotropic virus type I (HTLV-I) was the first described human retrovirus (1). In 1981, HTLV-I was established as the etiologic agent for adult T-cell leukemia (ATL) (2), a hematological malignancy first characterized in Japan (3). Since the initial description of ATL and the discovery of HTLV-I, the virus has been associated with an inflammatory, chronic, progressive neurologic disease known as HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP) in addition to several other inflammatory diseases (4–14). Although an increasing number of human diseases have been linked to HTLV-I the vast majority of HTLV-I—infected individuals remain clinically asymptomatic.
Source: Humana Press eBooks
Authors: Samantha S. Soldan, Steven Jacobson
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W138098744