Year: 2009
Type: article
Abstract: Androgenetic alopecia or baldness in men is clinically defined by symmetrical hair loss in the frontal hairline and scalp vertex. Development of androgenetic alopecia is genetically determined and dependent on the androgen receptor. The prevalence of this condition is thought to be as much as 50% in white males by age 50 years. Although there are no serious health consequences, hair loss can interfere with quality of life. The understanding of hair growth cycles andpathogenesis of androgenetic alopecia has increased markedly in the last years. The growth cycles of the preprogrammed scalp follicles shorten and the follicle thins, a process called miniaturization of the follicle. Many genes seem to be involved in this condition, but, to date, only the androgen receptor gene has been implicated. Many treatment options are available for male androgenetic alopecia and are summarized in this article; however, few of them have achieved effective results.
Source: Revista de Ciências Médicas
Institution: Universidade Federal do Paraná
Language: Portuguese
Topic: Hair Growth and Disorders
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W1408575179