Work

Acute and Impaired Wound Healing: Pathophysiology and Current Methods for Drug Delivery, Part 1 Normal and Chronic Wounds Biology, Causes, and Approaches to Care

Year: 2012

Type: article

Abstract: In Brief This is the first installment of 2 articles that discuss the biology and pathophysiology of wound healing, review the role that growth factors play in this process, and describe current ways of growth factor delivery into the wound bed. Part 1 discusses the latest advances in clinicians’ understanding of the control points that regulate wound healing. Importantly, biological similarities and differences between acute and chronic wounds are considered, including the signaling pathways that initiate cellular and tissue responses after injury, which may be impeded during chronic wound healing. In part 1 of this article series, the authors discuss the biology and pathophysiology of wound healing, review the role that growth factors play in this process, and describe current ways of growth factor delivery into the wound bed.

Source: Advances in Skin & Wound Care

DOI: 10.1097/01.asw.0000416006.55218.d0

Authors: Tatiana N. Demidova-Rice, Michael R. Hamblin, Ira M. Herman

Institutions: Massachusetts General Hospital, Healthpoint, National Institutes of Health

Language: English

Topic: Wound Healing and Treatments

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Allergy and Infectious Diseases