Work

Amidation and Cross-Linking of the Enzymatically Synthesized Peptidoglycan of Bacillus stearothermophilus

Year: 1974

Type: article

Abstract: A particulate enzyme system from Bacillus stearothermophilus which catalyzes the synthesis of peptidoglycan from uridine nucleotide precursors has been investigated. The preparation catalyzed extensive cross-linking of the enzymatically synthesized peptidoglycan. In addition in the presence of ATP and ammonia or l-glutamine amidation of the peptidoglycan also occurred. The nature of the amidated products obtained on lysozyme digestion of the enzymatically synthesized peptidoglycan was elucidated by a comparison with similar materials obtained after lysozyme digestion of isolated vegetative cell walls of this organism.

Source: Journal of Biological Chemistry

DOI: 10.1016/s0021-9258(19)42757-9

Authors: Paul E. Linnett, Jack L. Strominger

Institution: Harvard University

Language: English

Topic: Bacterial Genetics and Biotechnology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $3,430

OpenAlex ID: W1480648107

FWCI: 1.612

Cites: 38

Cited by: 31

Related to: 10