Work

Stimulation of the uptake of soluble proteins into isolated HeLa nuclei by pancreatic deoxyribonuclease

Year: 1975

Type: article

Abstract: The uptake into isolated HeLa nuclei of radioactive cytosol proteins and purified Escherichia coli ribosomal protein L7 is stimulated up to 4-fold by pancreatic deoxyribonuclease (DNase I). Similar effects are not observed with pancreatic ribonuclease A or phospholipase C. The results reported suggest that there is a general stimulatory effect of DNase on protein uptake by nuclei.

Source: Journal of Biological Chemistry

DOI: 10.1016/s0021-9258(19)41964-9

Authors: G S Cox, H Weissbach

Language: English

Topic: Nuclear Structure and Function

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,430

OpenAlex ID: W1482873977

FWCI: 0.195

Cites: 23

Cited by: 2

Related to: 10