Work

Swainsonine inhibits the biosynthesis of complex glycoproteins by inhibition of Golgi mannosidase II.

Year: 1982

Type: article

Abstract: In glycoprotein biosynthesis, rat liver Golgi mannosidases IA and IB are a-1,2-specific and convert Mans oligosaccharides to the corresponding Mans species, whereas mannosidase I1 cleaves a-1,3-and a-1,g-man-nosy1 residues from GlcNAcMan5 in completing the mannosyl trimming process (Tulsiani, D.

Source: Journal of Biological Chemistry

DOI: 10.1016/s0021-9258(18)34274-1

Authors: D R Tulsiani, T M Harris, O Touster

Institution: Vanderbilt University

Language: English

Topic: Glycosylation and Glycoproteins Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $3,430

OpenAlex ID: W1486483688

FWCI: 12.49

Cites: 20

Cited by: 463

Related to: 10