Proposing a Parkinson's disease–specific tremor scale from the MDS‐UPDRS
Year: 2015
Type: article
Study design: Observational Study
Abstract: BACKGROUND: This article proposes an International Parkinson and Movement Disorder Society (MDS)-UPDRS tremor-based scale and describes its measurement properties, with a view to developing an improved scale for assessing tremor in Parkinson's disease (PD). METHODS: This was a cross-sectional, multicenter study of 435 PD patients. Rasch analysis was performed on the 11 MDS-UPDRS tremor items. Construct validity, precision, and test-retest reliability were also analyzed. RESULTS: After some modifications, which included removal of an item owing to redundancy, the obtained MDS-UPDRS tremor scale showed moderate reliability, unidimensionality, absence of differential item functioning, satisfactory convergent validity with medication, and better precision than the raw sum score. However, the scale displayed a floor effect and a need for more items measuring lower levels of tremor. CONCLUSIONS: The MDS-UPDRS tremor scale provides linear scores that can be used to assess tremor in PD in a valid, reliable way. The scale might benefit from modifications and studies that analyze its responsiveness.
Source: Movement Disorders
DOI: 10.1002/mds.26271
Authors: Maria João Forjaz, Alba Ayala, Claudia M. Testa, Peter G. Bain, Rodger Elble, Dietrich Haubenberger, Carmen Rodriguez‐Blazquez, Günther Deuschl, Pablo Martinez‐Martin, for the International Parkinson and Movement Disorder Society Tremor Rating Scale Task Force
Institutions: Instituto de Salud Carlos III, Escuela Nacional de Sanidad, Virginia Commonwealth University, Imperial College London, SIU Medicine, Medical University of Vienna, Biomedical Research Networking Center on Neurodegenerative Diseases, Centro Nacional de Epidemiología, Christian-Albrechts-Universität zu Kiel
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W1487932308