Work

Uncovering a Role for SK2 in Angelman Syndrome

Year: 2015

Type: article

Abstract: Angelman syndrome is a severe neurodevelopmental disorder caused by mutations in UBE3A. Sun et al. (2015) report SK2 as a UBE3A substrate and provide insight into the molecular mechanisms that might underlie impaired neuronal function in individuals affected by Angelman syndrome.

Source: Cell Reports

DOI: 10.1016/j.celrep.2015.07.009

Authors: Sofia B. Lizarraga, Eric M. Morrow

Institutions: University of South Carolina, Brown University, Bradley Hospital

Language: English

Topic: Genetics and Neurodevelopmental Disorders

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $5,620