Year: 2012
Type: book-chapter
Abstract: CRP is phylogenetically a highly conserved plasma protein, with homolog in vertebrates and many invertebrates that participates in the systemic response to inflammation. Its plasma concentration increases during inflammatory states, a character that has long been employed for clinical purposes. CRP is a pattern recognition molecule, binding to specific molecular configurations that are typically exposed during cell death or found on the surfaces of pathogens. Its rapid increase in synthesis within hours after tissue injury or infection suggests that it contributes to host defense and that it is part of the innate immune response [8].
Source: InTech eBooks
DOI: 10.5772/47735
Authors: Moneer Faraj, Nihaya Salem
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W1489703162