Work

N2-Phenyl-9-(hydroxyalkyl)guanines and related compounds are substrates for Herpes simplex virus thymidine kinases.

Year: 2012

Type: article

Abstract: . The fact that HBPG is an efficient substrate is consistent, however, with its binding mode based both on molecular modeling studies and x-ray structure of the HBPG:TK complex.

Source: PubMed

Authors: Andrea Lossani, Lida Savi, Andrzej Manikowski, Andrew Maioli, Joseph Gambino, Federico Focher, Silvio Spadari, George E Wright

Institutions: Istituto di Genetica Molecolare, Glsynthesis

Language: English

Topic: Herpesvirus Infections and Treatments

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute of Allergy and Infectious Diseases

Award: DRUGS TO PREVENT RECURRENT HERPESVIRUS INFECTIONS

OpenAlex ID: W1492454011

FWCI:

Cites: 13

Cited by: 2

Related to: 10