Work

Biomarker Discovery in Animal Health and Disease: The Application of Post-Genomic Technologies

Year: 2007

Type: article

Abstract: SUMMARY: The causes of many important diseases in animals are complex and multifactorial, which present unique challenges. Biomarkers indicate the presence or extent of a biological process, which is directly linked to the clinical manifestations and outcome of a particular disease. Identifying biomarkers or biomarker profiles will be an important step towards disease characterization and management of disease in animals. The emergence of post-genomic technologies has led to the development of strategies aimed at identifying specific and sensitive biomarkers from the thousands of molecules present in a tissue or biological fluid. This review will summarize the current developments in biomarker discovery and will focus on the role of transcriptomics, proteomics and metabolomics in biomarker discovery for animal health and disease.

Source: Biomarker Insights

DOI: 10.1177/117727190700200040

Authors: Rowan E. Moore, Jennifer Kirwan, Mary K. Doherty, Phillip D. Whitfield

Institution: University of Liverpool

Language: English

Topic: Animal health and immunology

Subfield: Animal Science and Zoology

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,650