Work

Pathogenesis and immune response in tuberculous meningitis.

Year: 2014

Type: article

Abstract: Cerebral tuberculosis is the most severe type of extrapulmonary disease that is in developing countries highly predominant in children. Meningeal tuberculosis is the most common form and usually begins with respiratory infection followed by early haematogenous dissemination to extrapulmonary sites involving the brain. In comparison with the lung, Mycobacterium tuberculosis induces a very different immune response when infect the central nervous system. Herein, we review several aspects of the pathogenesis and immune response in pulmonary and cerebral tuberculosis in humans and experimental models and discuss the implications of this response in the cerebral infection outcome.

Source: Europe PMC (PubMed Central)

Authors: Bini Estela Isabel, Hernández Pando Rogelio

Institutions: Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Universiti Sains Malaysia

Language: English

Topic: Infectious Diseases and Tuberculosis

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: Universiti Sains Malaysia

OpenAlex ID: W1495088739

FWCI: 2.524

Cites: 41

Cited by: 34

Related to: 10