Work

Epidermal Growth Factor and a New Derivative

Year: 1972

Type: article

Abstract: A new procedure has been devised for the preparation of pure epidermal growth factor in high yield. The method involves a two-step column fractionation of crude extracts of the submaxillary gland obtained from adult male mice. Biologically active epidermal growth factor lacking the COOH-terminal Leu-Arg residues was also isolated.

Source: Journal of Biological Chemistry

DOI: 10.1016/s0021-9258(19)44568-7

Authors: C. Richard Savage, Stanley Cohen

Institution: Vanderbilt University

Language: English

Topic: HER2/EGFR in Cancer Research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

Open Access status: hybrid

Estimated APC paid: $3,430

OpenAlex ID: W1498071142

FWCI: 10.86

Cites: 5

Cited by: 1,206

Related to: 10