Year: 1999
Type: dissertation
Abstract: Respiratory diseases are a major cause of morbidity in preschool children. \nConfronted with young children with respiratory symptoms the physician \nfaces many uncertainties regarding the diagnosis, treatment and prognosis, \nnamely: \n• labelling of chronic and recurrent respiratory symptoms and defining 'asthma'; \n• the natural course of respiratory symptoms and the relation with future asthma; \nthe effectivity and side-effects of anti-asthma treatment, for both relief and prophylaxis; \n• the feasibility of and compliance with prophylactic inhalation therapy. \nIn studying effectivity of anti-asthma drugs, the investigator has additional problems: \n• symptoms as outcome measure; \n• the difficulty of conducting clinical trials, finding the appropriate setting and \nconsidering the ethical aspects of research in young children. \nIn this chapter, the background of these uncertainties for physicians and investigators \nwill be explored further. The place of sodium cromoglycate in prophylactic \ntherapy will be discussed in detail because it is the main focus of the studies in \nthis thesis. The results of this research will be presented in the following chapters \ntogether with results of studies on preschool asthma in general practice and on \nthe feasibility of and adherence to maintenance inhalation therapy.
Author: Marjolein Tasche
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W1498150220