Work

Normal CAG repeat variation at the DRPLA locus in world populations.

Year: 1995

Type: article

Study design: Observational Study

Abstract: Dentatorubral-pallidoluysian atrophy (DRPLA) is an autosomal dominant neurodegenerative disorder which became the seventh human genetic disorder shown to be caused by an expansion of a trinucleotide repeat. We have analyzed the distribution of CAG repeats at the DRPLA locus in 10 geographically and ethnically diverse populations. 18 refs., 1 fig., 1 tab.

Source: PubMed Central

Authors: R Deka, T Miki, S J Yin, S T McGarvey, M D Shriver, C H Bunker, S Raskin, J Hundrieser, R E Ferrell, R Chakraborty

Institution: University of Pittsburgh

Language: English

Topic: Genetic Neurodegenerative Diseases

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute on Aging, National Institute of General Medical Sciences

Awards: POPULATION GENETICS OF HUMAN HYPERVARIABLE LOCI, Population Mixture Effects on Genetic Variation, ADIPOSITY INSULIN ELECTROLYTES AND BLOOD PRESSURE

OpenAlex ID: W1499116327

FWCI: 0.791

Cites: 16

Cited by: 15

Related to: 10