Work

Preparing for first-in-man studies: the challenges for translational immunology post-TGN1412

Year: 2008

Type: article

Abstract: Current immunology research is generating many new approaches to immunotherapy. However, the recent disaster surrounding the testing of TGN1412, has unsettled regulators and the pharmaceutical industry regarding new immunotherapies and highlighted the complexities of conducting clinical trials with agents that target the immune system. Here we discuss the critical role for immunologists in ensuring that the development of new immunotherapies continues.

Source: Clinical & Experimental Immunology

DOI: 10.1111/j.1365-2249.2007.03559.x

Authors: C M Dayan, D C Wraith

Institution: University of Bristol

Language: English

Topic: Immunotherapy and Immune Responses

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: Wellcome Trust