Year: 2008
Type: preprint
Abstract: In this work we focus on how noise propagates in biochemical reaction networks and affects sensitivities of the system. We discover that the stochastic fluctuations can enhance sensitivities in one region of the value of control parameters by reducing sensitivities in another region. Based on this compensation principle, we designed a concentration detector in which enhanced amplification is achieved by an incoherent feedforward reaction network.
Source: arXiv (Cornell University)
Authors: Kim, Kyung Hyuk, Qian, Hong, Sauro, Herbert M.
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W1502926679