Year: 2004
Type: dissertation
Abstract: Whereas secondary prevention of cardiovascular events through risk factor\nmodification in patients with known coronary and carotid artery disease is recognised\nas cost-effective, CVD prevention by drug therapy in asymptomatic individuals has\nshown only modest benefits and to be relatively expensive. These interventions,\nhowever, could be cost-effective when targeting individuals at high risk for an event.\nBased on easily assessable risk factors, high-risk persons for cardiovascular disease\ncan be targeted.\nThe aim of the studies described in this thesis was to search for the most costeffective\nway to prevent cardiovascular disease in the general population. The studies\nare based on data from the Rotterdam Study, a population-based cohort study\ncomposed of 7,983 men and women aged 55 years and over who live in a welldefined\nsuburb of the city of Rotterdam, the Netherlands. Apart from the traditional\ncardiovascular risk factors, data were collected on the presence and severity of\natherosclerosis and the occurrence of cardiovascular events during follow-up.
Author: Rogier Nijhuis
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W1503282856