Work

Neurotoxicity of immunosuppressive therapies in organ transplantation.

Year: 2013

Type: article

Abstract: ABSTRACT: Immunosuppressive agents have revolutionized clinical transplantation medicine, allowing the avoidance of immune system attack on the transplanted graft. Nevertheless, the use of medications such as cyclosporine, tacrolimus and others also brought the side effects of these drugs. Early identification of drug-induced neurotoxicity in transplanted patients and of its specific causes is important, not only because of patient's poor clinical status but because of concomitant systemic and metabolic disorders which may obscure symptoms. Treatment and prognosis are highly dependent on the type of complication and it's early recognition. This review focuses on the clinical entities of neurotoxicity caused by immunosuppressive drugs in transplanted patients.

Source: Europe PMC (PubMed Central)

Authors: Daniela Anghel, Radu Tanasescu, Ana Campeanu, Ioana Lupescu, Giulio Podda, Ovidiu Bajenaru

Institutions: Carol Davila University of Medicine and Pharmacy, Institutul Clinic Fundeni, University of Nottingham, Spitalul Clinic Colentina

Language: English

Topic: Renal Transplantation Outcomes and Treatments

Subfield: Transplantation

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W1505630516

FWCI: 2.422

Cites: 22

Cited by: 94

Related to: 10