Work

Targeting DMARD resistance in Rheumatoid Arthritis

Year: 2008
Type: dissertation
Abstract: s (first author) 1. Van der Heijden JW, Oerlemans R, Tak PP, Scheper RJ, Scheffer GL, Assaraf YG, Lems WF, Dijkmans BAC, Jansen G. Expression of lung resistance protein on CD68 positive synovial tissue macrophages is associated with disease activity in rheumatoid arthritis patients. Arthritis & Rheumatism 54 (2006): S399-400. 2. Van der Heijden JW, Oerlemans R, Tak PP, Van der Laken CJ, Scheper RJ, Scheffer GL, Assaraf YG, Lems WF, Dijkmans BAC, Jansen G. Expression of multi-drug resistance related proteins in synovial tissue of rheumatoid arthritis patients: correlation with disease activity and methotrexate therapy. Annals of the Rheumatic Diseases 65 (2006): 340-341. 3. Van der Heijden JW, Oerlemans R, Lems WF, Scheper RJ, Dijkmans BAC, Jansen G. Potential anti-inflammatory properties elicited by the 26-S proteasome inhibitor bortezomib. Annals of the Rheumatic Diseases 65 (2006): 457. 4. Van der Heijden JW, Oerlemans R, Lems WF, Scheper RJ, Dijkmans BAC, Jansen G. The proteasome inhibitor bortezomib induces apoptosis and inhibits TNF-α release by activated T-cells from rheumatoid arthritis (RA) patients. Arthritis & Rheumatism 52 (2005): S261-262. 5. Van der Heijden JW, Oerlemans R, Tak PP, Smeets TJM, Scheper RJ, Scheffer GL, Assaraf YG, Lems WF, Dijkmans BAC, Jansen G. Expression of the multi-drug resistance protein BCRP in synovial tissue of RA- patients. A marker for inflammation or resistance to MTX? Arthritis & Rheumatism 52 (2005): S540-541. 6. Van der Heijden JW, Gerards, AH, Oerlemans R, Lems WF, Scheper RJ, Aarden LA, Dijkmans BAC, Jansen G. Inhibition of TNF-α production by activated T-cells of rheumatoid arthritis patients by novel anti-folate drugs: an ex vivo pilot study. Annals of the Rheumatic Diseases 64 (2005): 417. 7. Van der Heijden JW, Gerards AH, Oerlemans R, Lems WF, Scheper RJ, Aarden LA, Dijkmans BAC, Jansen G. Inhibition of tumor necrosis factor alpha production by activated T-cells of rheumatoid arthritis patients by novel anti-folate drugs: an ex vivo pilot study. Arthritis Research & Therapy 7 (2005): S261-262. Conference proceedings 1. Van der Heijden JW, Jansen G, Dijkmans BAC. Antifolate drug combinations for inflammatory diseases. In “Chemistry and Biology of Pteridines and Folates” (G Jansen & GJ Peters, eds), SHS Publications, Heilbronn, Germany (2007), 373-385. 2. Oerlemans R, Van der Heijden JW, Dijkmans BAC, Lems WF, Scheper RJ, Assaraf YG, Jansen, G. Sulfasalazine exposure confers MTX resistance in human monocytic/ macrophage cells by differential effects on folate influx and folate efflux systems. List of publications
Language: English
Subfield: Rheumatology
Field: Medicine
Open Access status: green
OpenAlex ID: W1507273039
Cites: 208
Cited by: 1
Related to: 10