Work

Genetic recombination in brome mosaic virus: effect of sequence and replication of RNA on accumulation of recombinants

Year: 1992

Type: article

Abstract: In order to facilitate the isolation of recombinants in brome mosaic virus, a series of duplication mutants with alterations in the RNA3 3' noncoding region has been engineered. The distribution of crossovers, which was observed to be dependent on the parental RNA3 sequence, supported the role of RNA structure in recombination. However, a negative correlation between replication of the parental RNA3 constructs and the accumulation of recombinant progeny confirmed the role of selection.

Source: Journal of Virology

DOI: 10.1128/jvi.66.11.6824-6828.1992

Authors: P D Nagy, J J Bujarski

Institution: Northern Illinois University

Language: English

Topic: Plant Virus Research Studies

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute of Allergy and Infectious Diseases

Awards: G3797268609, RECOMBINATION IN THE MULTIPARTITE RNA VIRUSES