Work

Roles of Homologous Recombination in Processing DNA Lesions

Year: 2007
Type: dissertation
Abstract: 8\n9\nScope of the Thesis\nScope of the Thesis\nThe abundance of DNA damaging agents poses a constant threat for genome stability. Therefore, cells have\nevolved multiple mechanisms to repair their DNA. The variety in possible DNA lesions that can occur\nrequire specified repair mechanism with the ability to remove particular types of lesions. For example,\nnucleotide excision repair removes lesions generated by UV-light whereas homologous recombination\nrepairs DNA double-stranded breaks induced by ionising radiation. However, the same type of DNA lesion\ncan be
Language: English
Open Access status: green
OpenAlex ID: W1508916030
Cites: 192
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Related to: 10