Work

Presumed case of "stiff-horse syndrome" caused by decreased gamma-aminobutyric acid (GABA) production in an American Paint mare.

Year: 2012

Type: article

Abstract: Glutamic acid decarboxylase (GAD) converts glutamic acid into the inhibitory neurotransmitter γ-aminobutyric acid (GABA). Increased serum GAD (auto) antibody concentrations were found in a mare with increased postural musculature tone resulting in stiffness and recumbence. The mare was treated with dexamethasone which resulted in resolution of clinical signs and decreased GAD antibody concentrations.

Source: PubMed Central

Authors: Tawna Backman Purcell, Ann Davidson Sellers, Lutz S Goehring

Institution: Colorado State University

Language: English

Topic: Autoimmune Neurological Disorders and Treatments

Subfield: Clinical Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W1512354399

FWCI: 0.399

Cites: 1

Cited by: 11

Related to: 10