Work

Mechanisms of chromosome segregation in meiosis – new views on the old problem of aneuploidy

Year: 2015

Type: article

Abstract: Errors in meiotic chromosome segregation are a leading cause of human aneuploidy. To explain the origin of aneuploidies we need to identify and understand the mechanisms that direct the proper segregation of homologous chromosomes. The four minireviews in this series provide a view on the function and regulation of systems that are in place to promote proper meiotic chromosome segregation.

Source: FEBS Journal

DOI: 10.1111/febs.13318

Author: Roberto J. Pezza

Institutions: Oklahoma Medical Research Foundation, University of Oklahoma Health Sciences Center, University of Oklahoma

Language: English

Topic: Microtubule and mitosis dynamics

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: March of Dimes Foundation, National Institutes of Health, National Institute of General Medical Sciences