Work

Inhibition of N-linked complex oligosaccharide formation by 1-deoxynojirimycin, an inhibitor of processing glucosidases.

Year: 1982

Type: article

Abstract: H3G I Y6Glucosidase activities which remove glucose residues from GlcZMangGlcNAcz and GlclManyGlcNAcz oligosaccharides were obtained in soluble form from Saccharomyces cerevisiae X-2180 without detergent.These two enzyme activities were clearly separated from the GlcsMangGlcNAcz oligosaccharide glucosidase which was shown previously to remove the terminal glucose residue from GlcsMan9GlcNAcz oligosaccharide (Kilker,

Source: Journal of Biological Chemistry

DOI: 10.1016/s0021-9258(19)45358-1

Authors: B Saunier, R D Kilker, J S Tkacz, A Quaroni, A Herscovics

Institutions: Harvard University, Drew University, Massachusetts General Hospital, Laboratoire de Biochimie, Institut du cancer Rosalind & Morris Goodman, McGill University

Language: English

Topic: Glycosylation and Glycoproteins Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $3,430

OpenAlex ID: W1515555384

FWCI: 7.098

Cites: 26

Cited by: 279

Related to: 10