Work

Crystallization and preliminary X-ray investigation of uridine phosphorylase from Escherichia coli.

Year: 1987

Type: article

Abstract: Crystals of uridine phosphorylase from Escherichia coli K12 have been grown from solutions of polyethylene glycol 4000. The crystals are trigonal, space group R3; the hexagonal axes are a = 154.4 A and c = 49.4 A. The crystals are quite stable to x-rays and diffract beyond 2.6 A resolution. It appears that the molecule is a hexamer with a subunit molecular weight of 27,500 and utilizes the 3-fold symmetry of the space group, resulting in two subunits/asymmetric unit.

Source: Journal of Biological Chemistry

DOI: 10.1016/s0021-9258(18)61584-4

Authors: W.J. Cook, G.W. Koszalka, W.W. Hall, S.V. Narayana, S.E. Ealick

Institutions: University of Alabama at Birmingham, UAB Medicine

Language: English

Topic: Enzyme Structure and Function

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $3,430

Funders: National Cancer Institute, National Institute of Dental and Craniofacial Research