Work

Autophagy and organelle turnover in Leishmania major

Year: 2012
Type: dissertation
Abstract: Leishmania are parasitic protozoa of medical and veterinary importance.They exist in various developmental forms that are morphologically and metabolically adapted to the different environmental conditions encountered as they are transferred between the insect vector and the mammalian host.Differentiation between developmental forms requires considerable cellular remodelling, which is associated with increased protein turnover.Autophagy is known to be important for this protein turnover, and thus for the successful differentiation and virulence of Leishmania.Autophagy is a eukaryotic intracellular degradation
Language: English
Field: Medicine
Open Access status: green
OpenAlex ID: W1518671373
Cites: 63
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Related to: 10