Work

The Function of YY1 and Its Oncogenic Role in Prostate Cancer

Year: 2013

Type: book-chapter

Abstract: Transcription factors regulate gene expression by interacting with specific DNA elements and other proteins to either activate or repress gene transcription. Aberrant expression and function of transcription factors are commonly observed in human cancers and play a pivo‐ tal role in oncogenic transformation. Ultimately, these affect downstream signaling path‐ ways, resulting in acquisition of some or all of the hallmarks of cancer, such as insensitivity to antigrowth or apoptotic signals, production of self-sufficient growth signals, limitless rep‐ licative potential and invasive or metastatic capability [1].

Source: InTech eBooks

DOI: 10.5772/53091

Authors: Daniel B., Guangchao Sui

Language: English

Topic: Prostate Cancer Treatment and Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: American Cancer Society, National Institutes of Health, National Cancer Institute

Awards: Dmp1-p53/YY1 interplays and their roles in lung cancer development, G5796563287, G9000200001