Work

Effect of silver ions on transport and retention of phosphate by Escherichia coli

Year: 1982
Type: article
Abstract: Silver ions inhibited phosphate uptake and exchange in Escherichia coli and caused efflux of accumulated phosphate as well as of mannitol, succinate, glutamine, and proline. The effects of Ag+ were reversed by thiols and, to a lesser extent, by bromide. In the presence of N-ethylmaleimide and several uncouplers, Ag+ failed to cause phosphate efflux, but still inhibited exchange of intracellular and extracellular phosphate, indicating an interaction at more than one site. It is unlikely that Ag+ caused metabolite efflux by acting solely as an uncoupler, as an inhibitor of the respiratory chain, or as a thiol reagent.
Language: English
Subfield: Genetics
Open Access status: green
OpenAlex ID: W1521089426
FWCI: 0.817
Cites: 32
Cited by: 296
Related to: 10