The Role of High-Sensitivity Troponin in Diagnosing Acute Coronary Syndromes
Year: 2014
Type: article
Abstract: The development of assays to detect plasma elevations of cardiac troponins has revolutionized our current clinical practice in the diagnosis and management of acute coronary syndromes. . Recently new highly sensitive assays for troponin measurement have been developed in an effort to detect even minimal elevations suggestive of subclinical injury providing thus the clinicians with additional diagnostic and prognostic information. These assays can facilitate an earlier diagnosis of myocardial ischemia or necrosis and add substantial prognostic information to improve our risk stratification and accordingly our treatment strategy. This increased sensitivity, however, may come in expense to decreased specificity. Nevertheless, accumulating evidence suggests that high sensitive troponins, if used appropriately regarding proper timing and evaluation of serial samples and in conjunction with clinical data can improve clinical care of patients with acute coronary syndromes
Author: Spyridon Koulouris
Institution: Bayreuth Medical Center
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W1526154727