Work

Heme A of cytochrome c oxicase. Structure and properties: comparisons with hemes B, C, and S and derivatives.

Year: 1975

Type: article

Abstract: Heme A, isolated from bovine heart muscle by procedures which include extractions into pyridine/chloroform and two-phase, liquid-liquid chromatography on Celite, has been converted to several derivatives. Examination of the proton nuclear magnetic resonance (PMR) spectra and other properties of these derivatives reveals heme A to be the iron complex of 8-formyl-6,-m-bis(2''-hydroxycarbonylethyl)-2-(1'-hydroxy-5',9',13'-trimethyl-4',8',12'-trans,trans-tetradecatrienyl)-1,3,5-trimethyl-4-vinylporphin. Substituents at the 2,4, and 8 positions are replaced by hydrogen in a resorcinol melt to give cytodeuteroporphin (8-demethyldeuteroporphyrin IX)...

Source: Journal of Biological Chemistry

DOI: 10.1016/s0021-9258(19)40860-0

Authors: WS Caughey, GA Smythe, DH O'Keeffe, JE Maskasky, MI Smith

Institutions: Arizona State University, Colorado State University

Language: English

Topic: Porphyrin and Phthalocyanine Chemistry

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $3,430

OpenAlex ID: W1526318680

FWCI: 10.93

Cites: 39

Cited by: 150

Related to: 10