Etiologic and diagnostic facets of Creutzfeldt-Jakob disease: The effect of genes and environment
Year: 2007
Type: dissertation
Abstract: Transmissible spongiform encephalopathies (TSE) or prion diseases constitute a \\nfascinating group of neurological disorders. In spite of their rarity, their unique \\netiopathological mechanisms and epidemiological aspects have attracted a considerable \\nnumber of researchers. \\n \\nThis thesis focuses on two facets: etiological mechanisms and diagnostic tests of \\nCreutzfeldt-Jakob disease (CJD). We have searched new insights into these two topics \\nusing genetic and classic epidemiological methodology. \\n \\nFor the studies presented in this book, we have used data from the Dutch, Italian \\nand UK CJD National Surveillance Systems, the \\'European collaborative Study group of \\nCJD\\' (EUROCJD), the \\'extended European collaborative Study group of CJD\\' \\n(NEUROCJD), the \\'Early clinical diagnosis of human spongiform encephalopathies by \\nanalysis of biological fluids-CJD Markers collaboration\\' (EPICJD), and the \\'Rotterdam \\nStudy\\'.
Author: Pascual Sánchez‐Juan
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W1527274796