Work

Co‐ordination of cough and swallow in vivo and in silico

Year: 2011

Type: review

Abstract: Coughing and swallowing are airway-protective behaviours. The pharyngeal phase of swallowing prevents aspiration of oral material (saliva, food and liquid) by epiglottal movement, laryngeal adduction and clearing of the mouth and pharynx. Coughing is an aspiration-response behaviour that removes material from the airway. Co-ordination of these behaviours is vital to protect the airway from further aspiration-promoting events, such as a swallowing during the inspiratory phase of coughing. The operational characteristics, primary strategies and peripheral inputs that co-ordinate coughing and swallowing are unknown. This lack of knowledge impedes understanding and treatment of deficits in airway protection, such as the co-occurrence of dystussia and dysphagia common in Parkinson's and Alzheimer's diseases, as well as stroke.

Source: Experimental Physiology

DOI: 10.1113/expphysiol.2011.063362

Authors: Teresa Pitts, Kendall Morris, Bruce Lindsey, Paul Davenport, Ivan Poliacek, Donald Bolser

Institutions: University of Florida, University of South Florida, Comenius University Bratislava

Language: English

Topic: Respiratory and Cough-Related Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute, National Center for Advancing Translational Sciences