Year: 1998
Type: other
Abstract: β-adrenoceptor blocking drugs are widely used for the treat-ment of cardiovascular diseases such as arterial hypertension, coronary heart disease and supraventricular and ventricular tachyarrhythmias. They may also be beneficial in the hyper-kinetic heart syndrome, hypotensive circulatory disorders, portal hypertension, hyperthyroidism, tremour, migraine, anxiety, psychosomatic disorders or glaucoma. In recent years even patients with heart failure have been successfully treated with β-blockers initially given at very low doses. A great number of β-adrenoceptor blocking drugs are now available for clinical use which differ widely with respect to their pharmacodynamic and pharmacokinetic properties [1, 2]. They all interact with β-adrenoceptors forming drug receptor complexes so that endogenous norepinephrine and epinephrine are hindered from accessing the receptor. This
Author: U. Borchard
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W1527768859