Prevalence and trend of HIV infection among voluntary blood donors in China since implementation of the Blood Donation Law: a systematic review and meta‐analysis
Year: 2012
Type: review
Study designs: Systematic Review, Meta-Analysis
Abstract: OBJECTIVE: In 1998, the Blood Donation Law was enacted in China in response to the outbreak of HIV endemic in central rural China as a result of unhygienic and commercial blood collection. This study aims to provide a first comprehensive review of available data on the prevalence, trend and other epidemiological characteristics of HIV infection among voluntary blood donors since 1998. METHODS: Major English and Chinese databases were searched and a systematic review was constructed. Pooled infection rates by province and year were calculated using random-effect or fixed-effect models. RESULTS: A total of 87 studies met our inclusion criteria. A total of 2573 HIV-positive cases were identified among voluntary blood donors in the past 10 years; the pooled prevalence was 13.22/100,000, with a range of 0.74-125.97 per 100,000. Among the 24 provinces that reported yearly data, the prevalence of HIV increased from 5.62/100,000 to 28.90/100,000. The male-to-female ratio was 2.8; about 60% were below the age of 30 years. CONCLUSIONS: The prevalence of HIV in voluntary blood donors has risen steadily and fast. Efficient measures need to be taken urgently to prevent HIV test-seeking through blood donor programmes, to promote voluntary blood donation in low-risk groups and to enforce the Blood Donation Law strictly.
Authors: Yan Hong, Xia Huang, Hua Ling, Hongwen Liao
Institutions: Texas A&M Health Science Center, Texas A&M University
Language: English
Subfield: Management of Technology and Innovation
Domain: Social Sciences
Open Access status: bronze
OpenAlex ID: W1528692845