Year: 1997
Type: dissertation
Abstract: Breast cancer is the most conmlon malignant tumor among women, with an\nestimated 135,000 new cases and 58,000 recorded deaths per year in the Europeau\nCommunity in 1990. With respect to the Netherlands, the most recent data of The\nNetherlands Cancer Registry show an incidence of nearly 10.000 new cases of primary\nbreast cancer and about 3500 breast cancer deaths per year. In women breast\ncancer comprises one-third (33,2%) of all types of cancer. Ultimately about one out\nof 10 women wiII get breast cancer during her life and one out of every 22 women\nwiII sooner or later die as a consequence of metastatic disease.\nAmong the solid tumors breast cancer is one of the few types of cancers sensitive to\ndifferent systemic treatment reginJens both with respect to endocrine- and\nchemotherapy. Both treatment modalities are nowadays standard practice in the\ntreatment of breast cancer, either to achieve cure, or prolongation of (relapse-free)\nsurvival in the adjuvant setting, or to palliate metastatic disease. The efficacy of the\ndifferent forms of systemic treatment is dependent on patients- and tumor\ncharacteristics.
Author: M. Bontenbal
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: green
Funder: KWF Kankerbestrijding
OpenAlex ID: W1531927793