Work

A Survey of Oxidative Paracatalytic Reactions Catalyzed by Enzymes that Generate Carbanionic Intermediates: Implications for ROS Production, Cancer Etiology, and Neurodegenerative Diseases

Year: 2011

Type: other

Abstract: This chapter contains sections titled: Overview Paracatalytic Reactions: Definition Discovery of Enzyme-Catalyzed Oxygenase Side Reactions: Rubisco Reaction of Carbanions with Oxygen Catalyzed by Selected Enzymes (Excluding Pyridoxal 50′-Phosphate-Containing Enzymes) Oxidation Reactions Catalyzed by PLP-Containing Amino Acid Decarboxylases Mechanisms Contributing to the Oxidation Reactions Catalyzed by PLP-Containing Amino Acid Decarboxylases Paracatalytic Oxidation of the α-Ketoglutarate Dehydrogenase-Generated Carbanion Potential Role of Paracatalytic Side Reactions in Diseases Conclusions Acknowledgements References

Source: Advances in enzymology and related areas of molecular biology/Advances in enzymology and related subjects

DOI: 10.1002/9780470920541.ch7

Authors: Victoria I. Bunik, John V. Schloss, John T. Pinto, Natalia Dudareva, Arthur J. L. Cooper

Institutions: Lomonosov Moscow State University, University of New England, New York Medical College, Purdue University West Lafayette

Language: English

Topic: Metal-Catalyzed Oxygenation Mechanisms

Subfield: Inorganic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute on Aging, National Institute of General Medical Sciences

Awards: Mitochondiral enzymes/oxidative stress in Alzheimer's, Mitochondrial and Metabolic Dysfunction in Age-related Neurodegeneration, G3987313054, G5375199449, G548514458, OXYGENASE SIDE REACTIONS OF CARBANION FORMING ENZYMES

OpenAlex ID: W1534122861

Cites: 119

Cited by: 27

Related to: 10